A number of hereditary ataxias are caused by inborn butterfly cupcake liners errors of metabolism (IEM), most of which are highly heterogeneous in their clinical presentation.Prompt diagnosis is important because disease-specific therapies may be available.In this review, we offer a comprehensive overview of metabolic ataxias summarized by disease,
The endocrine and exocrine cells in pancreas originate initially from a group of apparently identical endoderm cells in the early pubis yeti gut.The endocrine and exocrine tissues are composed of islet/acinar and duct cells respectively.To explore the mechanism of pancreas cell fate decisions, we first construct a minimal mathematical model related
Hepatic tuberculosis can manifest in various forms, including parenchymal, serohepatic, tuberculous cholangitis and mixed form.Isolated hepatic tuberculosis, specifically in the form of serohepatic tuberculosis, is very rare.Patients with hepatic tuberculosis often present with nonspecific symptoms such as abdominal pain, weight loss, night fever,
IL-17 is a cytokine produced by innate and acquired immunity cells that have an action against fungi and bacteria.However, its action in helminth infections is unclear, including in Toxocara canis infection.Toxocariasis is a neglected zoonosis representing a significant public health problem with an estimated seroprevalence of 19% worldwide.In the